This study investigates the preparation of mPEG-PLA diblock copolymers through a controlled polymerization technique. Various reaction conditions, including catalyst type, were optimized to achieve desired molecular weights and polydispersity indices. The resulting copolymers were analyzed using techniques such as high-performance liquid chromatogr

Poly(lactic acid) PLA (PLA) is a versatile biocompatible polymer widely used in drug delivery systems. However, its rapid degradation and poor water solubility limit its efficacy. To overcome these challenges, PEGylation, the process of attaching polyethylene glycol Polyethylene Glycol, has emerged as a promising strategy. Biocompatible PEGylation